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Respiratory Therapeutics For Pulmonary Arterial Hypertension
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Please select the best answer for each queston.
1: following hemodynamic values indicates the presence of pulmonary arterial hypertension?
Pulmonary arterial occlusion pressure = 10 mm Hg
Mean aortic pressure = 100 mm Hg
Mean pulmonary arterial pressure = 30 mm Hg
Central venous pressure = 7 mm Hg
2: The World Health Organization (WHO) developed classifications of pulmonary arterial hypertension (PAH) based on:
functional level
etiology
pathology
manifestations
3: Routine, general management for PAH includes all of the following, EXCEPT:
vasopressors
supplemental oxygen
diuretics
anticoagulants
4: A phosphodiesterase inhibitor that is AEROSOLIZED for management of PAH is ______.
milrinone (Primacor)
nefedipine (Procardia)
sildenafil (Viagra)
bosentan (Tracleer)
5: Reperfusion of ischemic myocardium resulting from procedures, like angioplasty, can cause PAH by which mechanism?
phosphodiesterase inhibition
catecholamine suppression
nitric oxide release
endothelin release
6: In young persons, pulmonary hypertension, accompanying a congenital anatomic shunt, often mimics _____.
pulmonary fibrosis
myocardial infarction
asthma
pulmonary edema
7: The indications for prostacyclin therapy for PAH include which of the following?
PAH WHO Group I
NYHA class III and IV
Failure of other, standard therapeutics
All of the above
8: The duration of action for epoprostenol (Flolan) is:
3-5 minutes
30-60 minutes
60-120 minutes
120-180 minutes
9: The Respironics (TM) Prodose and I-neb nebulizers are intended to deliver which medication?
nitric oxide
iloprost (Ventavis)
bosentan (Tracleer)
epoprostenol (Flolan)
10: All of the following correctly applies to Flolan aerosol delivery in the acute care setting, EXCEPT:
The solution must be shielded from light.
Drug delivery should be suspended for transports.
Systemic hypotension may occur as a side effect.
The pharmacist is responsible for reconstitution of the drug.
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